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Non-Compliance With Treatment in Patients Suffering From Schizophrenia: a Study To Evaluate Possible Contributing Factors

Vimal K. Sharma

Kishore Kumar K.V.

Derek Lowe

Background. Various factors have been associated with non-compliance with treatment in schizophrenia. The aim of this study was to examine this association using standardised measures.

Method. Compliance was determined and socio-demographic and illness variables recorded. Insight, subjective response to medication and relatives' knowledge and attitude about schizophrenia were measured.

Results. Non-compliant patients were younger, had shorter durations of illness, had an episodic course of illness, reported side-effects less frequently, made incorrect attributions to current positive symptoms more frequently and had a more negative subjective response to medication. Key relatives of non-compliant patients were more often employed.

Conclusions. Patients need to experience for themselves the merits of taking medication before accepting the need to take them long-term. Psychoeducational and cognitive-behavioural interventions need to be targeted at changing attribu tions to current positive symptoms. The presence of a key person in the community is crucial to improve compliance.

International Journal of Social Psychiatry, Vol. 44, No. 2, 92-106 (1998)
DOI: 10.1177/002076409804400202


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